Articles

Beta-Glucuronidase in the Hydrolysis of Glucuronide-Drug Conjugates

Beta-Glucuronidase in the Hydrolysis of Glucuronide-Drug Conjugates

The useful application of Beta-Glucuronidase in hydrolysis of glucuronides. Organic mechanism of glucuronide conjugate hydrolytic cleavage.

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Crosslinking Proteins With DTSSP

Crosslinking Proteins With DTSSP

This article describes some of the useful features of the homobifunctional crosslinker 3,3'-Dithiobis (sulfosuccinimidyl propionate), also known...

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Fundamentals of Choosing a MALDI Matrix

Fundamentals of Choosing a MALDI Matrix

MALDI is a commonly employed technique for analyzing proteins and other biomolecules by mass spectrometry. This soft ionization technique can be...

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Liquid Chromatography: Mobile Phases for LCMS

Liquid Chromatography: Mobile Phases for LCMS

This article describes some important aspects of selecting the best mobile phase for a specific application. Posting also covers some of the mor...

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Sulfo-NHS and NHS Esters in Protein Chemistry

Sulfo-NHS and NHS Esters in Protein Chemistry

This article describes the reaction of Sulfo-NHS esters with proteins and peptides in buffered reaction systems. Several of the key reactio...

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