Other Protein Modifiers
Protein Modification Reagents
2-Iminothiolane hydrochloride (Traut's Reagent) is used to convert primary amine (-NH2) groups to sulfhydryl groups (-SH) at pH 7 to 10. Traut's reagent (2-IT) is a water soluble molecule that is easy to use and creates a wide range of flexibility to the researcher.
N-succinimidyl-S-acetyl-thioacetate (SATA) is a protein modification reagent used to convert lysines to protected sulfhydryls (-SH), which can be activated by the use of hydroxylamine.
Sulfo-NHS Acetate (Sulfosuccinimidyl acetate) is a protein modification reagent used to irreversibly block lysine residues.