Other Protein Modifiers

Other Protein Modifiers

Protein Modification Reagents

Products

2-Iminothiolane

2-Iminothiolane hydrochloride (Traut's Reagent) is used to convert primary amine (-NH2) groups to sulfhydryl groups (-SH) at pH 7 to 10. Traut's reagent (2-IT) is a water soluble molecule that is easy to use and creates a wide range of flexibility to the researcher.

14104-500

$69.00

Citraconic Anhydride

Citraconic Anhydride (Methylmaleic anhydride) is used to block primary amine (-NH2) groups at pH 7 to 9. Citraconic anhydride reacts with primary amines to create a reversible amide linkage, which can be reversed under acidic conditions or in the presence of hydroxylamine.

14105-25

$49.00

Hydroxylamine Hydrochloride

Hydroxylamine Hydrochloride (Hydroxylamine HCl) is a widely used reducing agent used in biomolecular applications. Hydroxylamine HCl is used for reducing EGS crosslinkers and deprotecting SATA protected proteins.

11304-25

$19.00

Iodoacetamide (IAA)

Iodoacetamide (IAA)

14107-5x10

$49.00

Maleimide > 99%

Maleimide (2,5-Pyrroledione) is a five member ringed compound that is commonly used in synthetic applications and as a synthetic starting material for cysteine blocking, Diels-Alder synthesis, and through Michael addition.

11306-5

$19.00

N-Ethoxycarbonylmaleimide

N-Ethoxycarbonylmaleimide is used in synthetic applications and in protein reactions. This compound can be used in reactions involving Diel-Alder reactions, Michael additions and can be utilized to introduce a maleimide group into a peptide or protein.

11308-1

$37.00

N-Ethylmaleimide (NEM)

N-ethylmaleimide (NEM) is a protein modifying chemical reagent used to protect or block sulfhydryl groups.

11305-5

$29.00

N-Methoxycarbonylmaleimide

N-Methoxycarbonylmaleimide is a compound used in synthetic applications, including Diel-Alder reactions, and can be used to introduce a maleimide group onto a peptide or protein.

11307-1

$39.00

N-succinimidyl-S-acetyl-thioacetate (SATA)

N-succinimidyl-S-acetyl-thioacetate (SATA) is a protein modification reagent used to convert lysines to protected sulfhydryls (-SH), which can be activated by the use of hydroxylamine.

14102-100

$67.00

Sulfo-NHS Acetate

Sulfo-NHS Acetate (Sulfosuccinimidyl acetate) is a protein modification reagent used to irreversibly block lysine residues.

14103-100

$72.00

TCEP-HCL

Tris(2-carboxyethyl) phosphine (TCEP) is a reducing agent that is frequently used to reduce disulfide bonds found between cysteine residues in proteins and in disulfide bonds found in proteins crosslinked with DTSSP (CovaChem 13304) or DSP (CovaChem 13303).

11303-1

$29.00