LCMS and HPLC Additives

LCMS and HPLC Additives

LCMS Mobile Phase Chromatography additives can make a drastic improvement in both separations and ionization. The level of product refinement is critical to the successfully implementing mobile phase additives into your chromatagraphy and spectrometry applications. CovaChem's LCMS and HPLC additives are some of the most highly refined chemicals in the industry, making them ideally suited for sensitive HPLC and LCMS applications.

One of the pre-requisites for LCMS buffers is that the mobile phases prepared, and all mobile phase additives, should be volatile. This is one of the reasons why buffers such as Sodium Phosphate are not commonly relied upon for LCMS applications. Although many inorganic buffers lend themselves to excellent separations and effectively mask charged groups which cause poor peak shape (ie. tailing and fronting), they are typically unsuitable for LCMS due to their lack of volatility.

CovaChem offers a variety of UltraPure LCMS Grade volatile buffer additives that are compatible with LCMS, HPLC, and proteomics applications, including: Trifluoracetic acid (TFA), Formic acid plus TFA, Acetic acid, Formic acid, Heptafluorobutyric acid (HFBA), Triethylamine (TEA), Propionic acid

In both LCMS and HPLC applications, it is critical that mobile phases consistent of very highly refined components that are free of interfering contaminants, metal contaminants, and other non-volatiles. Consistent composition of mobile phases is also important, as small variations in concentration and pH can be the difference between adequate separation or not. Not only does CovaChem carry the highest quality buffers for LCMS and HPLC applications, but it is conveniently packaged in multiple packaging sizes, including 1 mL ampules, for easily and accurately preparing one liter of 0.1 % buffers in either water or organic phases. CovaChem also offers custom ampule packaging, for your own mixture and volumes. Call today +1-815-315-1271 for more information.

Products

LCMS Grade Acetic Acid (UltraPure)

LCMS Grade Acetic Acid (CAS# 64-19-7) from CovaChem is of Ultra High Purity ideally suited for sensitive LCMS and HPLC applications.

11201-10x1

$32.00

LCMS Grade Ammonium Formate

LCMS Grade Ammonium Formate (CAS# ‎540-69-2) from CovaChem is of Ultra High Purity ideally suited for sensitive LCMS and HPLC applications.

19111-10pk

$89.00

LCMS Grade Ammonium Formate (10 M Solution)

LCMS Grade Ammonium Formate Solution (10 M Liquid) from CovaChem is of highly refined and ideally suited for sensitive LCMS and HPLC applications.

19221-25

$35.00

LCMS Grade Formic Acid (UltraPure)

LCMS Grade Formic Acid (CAS# 64-18-6) from CovaChem is of Ultra High Purity ideally suited for sensitive LCMS and HPLC applications.

11202-10x1

$32.00

LCMS Grade Formic Acid plus TFA (UltraPure)

LCMS Grade Formic Acid with TFA from CovaChem is of Ultra High Purity ideally suited for sensitive LCMS and HPLC applications. This mixture offers the ability to quickly and easily make one liter of 0.1% Formic Acid with 0.01% TFA enabling the exceptional resolving powers of Trifluoroacetic acid (TFA) without reducing ionization efficiencies.

11207-10x1

$42.00

LCMS Grade HFBA (UltraPure)

LCMS Grade Formic Acid (CAS# 375-22-4) from CovaChem is of very high purity and well suited for HPLC and LCMS applications, where separations are difficult otherwise.

11203-10x1

$43.00

LCMS Grade Propionic acid (UltraPure)

LCMS Grade Propionic acid (Ultra High Purity) from CovaChem is well suited for HPLC and LCMS applications. Propionic acid can be used as a mobile phase for HPLC or LCMS, or can be used post-column in LCMS applications to increase ionization efficiencies when ion pairing agents are used for separation.

11206-10x1

$39.00

Triethylamine (UltraPure)

LCMS Grade Triethylamine (Ultra High Purity) from CovaChem is well suited for HPLC and LCMS applications, where separations are difficult.

11205-10x1

$41.00

Trifluoroacetic Acid (LCMS Grade TFA)

LCMS Grade TFA (Ultra High Purity) from CovaChem is well suited for HPLC and LCMS applications, where separations are difficult otherwise.

11204-10x1

$35.00