SPDP Crosslinker
Description
N-succinimidyl-3-(2-pyridyldithio)propionate (SPDP Crosslinker) is a cleavable heterobifunctional crosslinker. SPDP contains a dithiopyridyl group which is reactive towards cyteines (-SH groups) and an NHS group, which is useful when targetting primary amines (-NH2 groups). SPDP also contains a disulfide linkage in its spacer arm, which is cleavable with reducing agent, such as DTT, TCEP, among a few others carried by CovaChem. Package Sizes: 100 mg and 1 gram Product Numbers: 13411-100mg and 13411-1g Product Name: SPDP Crosslinker Alternative Names: SPDP; SPDP Crosslinker; 68181-17-9; N-succinimidyl-3-(2-pyridyldithio)propionate; 3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester; 3-(2-Pyridyldithio)propionic acid NHS ester; C12H12N2O4S2
Specifications Appearance: White Solid Purity: is ≥ 95% by quantitative NMR Storage: 4 °C, protected from moisture
State: Solid CAS#: 68181-17-9 Chemical Formula: C12H12N2O10 Molecular Weight: 312.36 Spacer length: 6.4 Å Melting Point: 84-86 °C (Lit) Country of Origin: USA Tariff Code: 2933.99.7900 Additional Product Information: |