DSG Crosslinker

DSG Crosslinker

Description Price Quantity Buy
Package Sizes: 100 mg
SKU: 13301-100
Package Sizes: 5 x 100 mg
SKU: 13301-5x100
Package Sizes: 1 gram
SKU: 13301-1
Disuccinimidyl glutarate (DSG) is a cell membrane permeable, homobifunctional crosslinker with a five carbon spacer arm. DSG contains two NHS esters that are ideal for selectively targeting primary amine moieties at pH 7 to 9. DSG is a simple, short length crosslinker that forms irreversible amide bonds with lysine residues. This compound is ideally suited for a wide range of crosslinking applications, where a cleavable crosslinker is not preferential.

This compound is also available in a water soluble form (BS2G), which enables direct addition to aqueous buffers, when the user prefers not to use any organic solvents in their crosslinking applications.

CovaChem's DSG is among the highest purity in the industry, with an absolute purity specification of ≥ 97%, measured with quantitative NMR against an internal standard, and typical batches have purity values close to 99% pure.

Package Sizes: 100 mg and 1 gram

Product Numbers: 13301-100 and 13301-1

Product Name: DSG Crosslinker

Alternative Names: DSG, discuccinimidyl glutarate, DSG crosslinker, Succinimidyl glutarate, Di(N-succinimidyl) glutarate, 2,5-dioxopyrrolidin-1-yl 6-(2,5-dioxopyrrolidin-1-yl)-5-oxohexanoate; C13H14N2 O8


Appearance: White Solid

Purity: is ≥ 97% by quantitative NMR

Storage: 4 °C, protected from moisture


Properties Physical State: Solid

CAS#: 79642-50-5

Chemical Formula: C13H14N2 O8

Molecular Weight: 326.26

Spacer length: 7.7 Å

Melting Point: 142-145 °C (Lit)

Country of Origin: USA

Tariff Code: 2928.00.5000

Additional Product Information:
DSG Product Information Bulletin
DSG Crosslinker MSDS
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