SPDP Crosslinker

SPDP Crosslinker

Description Price Quantity Buy
Package Size: 100 mg
SKU: 13411-100
Package Size: 1 gram
SKU: 13411-1
N-succinimidyl-3-(2-pyridyldithio)propionate (SPDP Crosslinker) is a cleavable heterobifunctional crosslinker. SPDP contains a dithiopyridyl group which is reactive towards cyteines (-SH groups) and an NHS group, which is useful when targetting primary amines (-NH2 groups). SPDP also contains a disulfide linkage in its spacer arm, which is cleavable with reducing agent, such as DTT, TCEP, among a few others carried by CovaChem.

Package Sizes: 100 mg and 1 gram

Product Numbers: 13411-100mg and 13411-1g

Product Name: SPDP Crosslinker

Alternative Names: SPDP; SPDP Crosslinker; 68181-17-9; N-succinimidyl-3-(2-pyridyldithio)propionate; 3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester; 3-(2-Pyridyldithio)propionic acid NHS ester; C12H12N2O4S2


Appearance: White Solid

Purity: is ≥ 95% by quantitative NMR

Storage: 4 °C, protected from moisture


Properties Physical State: Solid

CAS#: 68181-17-9

Chemical Formula: C12H12N2O10

Molecular Weight: 312.36

Spacer length: 6.4 Å

Melting Point: 84-86 °C (Lit)

Country of Origin: USA

Tariff Code: 2933.99.7900

Additional Product Information:
SPDP Crosslinker Product Information Bulletin
SPDP Crosslinker MSDS
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DSS Crosslinker