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SMCC Crosslinker
Category: Heterobifunctional Crosslinkers
Description
SMCC is a heterobifunctional protein crosslinker. SMCC is commonly used to prepare antibody-enzyme conjugates. This molecule contains an amine reactive NHS ester on one end, and a maleimide functional group that can be utilized to react specifically with sulfhydryl (-SH) moeities. The maleimide functional group does not readily react with amino group (-NH2) as found on lysine residues, thus maleimide activated conjugates can be readily formed and preserved for later utilization.
Package Sizes: 100 mg and 1 gram Product Numbers: 13409-100mg and 13409-1g Product Name: SMCC Crosslinker Alternative Names: SMCC; SMCC Crosslinker; 64987-85-5; 4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester; N-Succinimidyl 4-(maleimidomethyl)cyclohexanecarboxylate; C16H18N2O6
Specifications Appearance: White Solid Purity: is ≥ 90% by quantitative NMR Storage: 4 °C, protected from moisture
Properties Physical State: Solid CAS#: 64987-85-5 Chemical Formula: C16H18N2O6 Molecular Weight: 334.32 Spacer length: 8.3 Å Melting Point: 180-182 °C (Lit) Country of Origin: USA Tariff Code: 2928.00.5000 Additional Product Information: SMCC Crosslinker Product Information Bulletin SMCC Crosslinker MSDS |