DSG Crosslinker

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DSG Crosslinker DSG Crosslinker
Package Sizes: 100 mg
SKU: 13301-100
WEIGHT: 0.20
$32.00
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DSG Crosslinker DSG Crosslinker
Package Sizes: 5 x 100 mg
SKU: 13301-5x100
WEIGHT: 0.20
$140.00
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DSG Crosslinker DSG Crosslinker
Package Sizes: 1 gram
SKU: 13301-1
WEIGHT: 0.20
$259.00
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Disuccinimidyl glutarate (DSG) is a cell membrane permeable, homobifunctional crosslinker with a five carbon spacer arm. DSG contains two NHS esters that are ideal for selectively targeting primary amine moieties at pH 7 to 9. DSG is a simple, short length crosslinker that forms irreversible amide bonds with lysine residues. This compound is ideally suited for a wide range of crosslinking applications, where a cleavable crosslinker is not preferential.

This compound is also available in a water soluble form (BS2G), which enables direct addition to aqueous buffers, when the user prefers not to use any organic solvents in their crosslinking applications.

CovaChem's DSG is among the highest purity in the industry, with an absolute purity specification of ≥ 97%, measured with quantitative NMR against an internal standard, and typical batches have purity values close to 99% pure.

Package Sizes: 100 mg and 1 gram

Product Numbers: 13301-100 and 13301-1

Product Name: DSG Crosslinker

Alternative Names: DSG, discuccinimidyl glutarate, DSG crosslinker, Succinimidyl glutarate, Di(N-succinimidyl) glutarate, 2,5-dioxopyrrolidin-1-yl 6-(2,5-dioxopyrrolidin-1-yl)-5-oxohexanoate; C13H14N2 O8

Specifications

Appearance: White Solid

Purity: is ≥ 97% by quantitative NMR

Storage: 4 °C, protected from moisture

Properties

Properties Physical State: Solid

CAS#: 79642-50-5

Chemical Formula: C13H14N2 O8

Molecular Weight: 326.26

Spacer length: 7.7 Å

Melting Point: 142-145 °C (Lit)

Country of Origin: USA

Tariff Code: 2928.00.5000


Additional Product Information:
DSG Product Information Bulletin
DSG Crosslinker MSDS
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  • DryBlend PBS (Phosphate Buffered Saline), pH 7.2

    Phosphate buffered saline is used as a buffer in protein crosslinking and protein modification reactions.
    $43.00
  • DSS Crosslinker

    Disuccinimidyl Suberate (DSS) is a homobifunctional crosslinker that reacts with primary amines.
    $32.00
  • EDC-HCL | EDAC-HCL | > 99%

    N-Ethyl-N'(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC-HCl) is a zero length protein crosslinker. Also known as EDAC-HCl, this reagent is often used with either Sulfo-NHS (CovaChem 13505) or NHS (CovaChem 13504). EDC functions by activating the carboxyl region of the protein or other molecule, and coupling it to an amine or other nucleophilic functional group.
    $19.00
  • Hexafluoroisopropanol (HFIP)

    Hexafluoroisopropanol (HFIP) is also called 1,1,1,3,3,3-Hexafluoro-2-propanol or HFIP. HFIP is an acylation reagent that is used to introduce fluorine atoms into a compound and improve volatility. This is useful for Gas Chromatography (GC) applications and GCMS applications.
    $38.00
  • HPLC Grade Water

    CovaChem's HPLC Grade water is refined for optimal performance in High Performance Liquid Chromatography.
    $29.00
  • LC-SPDP Crosslinker

    Succinimidyl 6-[3-(2-pyridyldithio)propionamido] hexanoate (LC-SPDP) is a heterobifunctional crosslinker that is amino reactive on one end and sulfhydryl reactive on the other end. LC-SPDP contains a long spacer arm (15.7 Å)for increased molecular flexibility and a reducible disulfide, which is allows for cleavage of the crosslinker after crosslink formation.
    $197.00
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