DSG Crosslinker

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DSG CrosslinkerDSG Crosslinker
Package Sizes: 100 mg
SKU: 13301-100
WEIGHT: 0.20
$45.00
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DSG CrosslinkerDSG Crosslinker
Package Sizes: 1 gram
SKU: 13301-1
WEIGHT: 0.20
$399.00
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Disuccinimidyl glutarate (DSG) is a cell membrane permeable, homobifunctional crosslinker with a five carbon spacer arm. DSG contains two NHS esters that are ideal for selectively targeting primary amine moieties at pH 7 to 9. DSG is a simple, short length crosslinker that forms irreversible amide bonds with lysine residues. This compound is ideally suited for a wide range of crosslinking applications, where a cleavable crosslinker is not preferential.

This compound is also available in a water soluble form (BS2G), which enables direct addition to aqueous buffers, when the user prefers not to use any organic solvents in their crosslinking applications.

CovaChem's DSG is among the highest purity in the industry, with an absolute purity specification of ≥ 97%, measured with quantitative NMR against an internal standard, and typical batches have purity values close to 99% pure.

Package Sizes: 100 mg and 1 gram

Product Numbers: 13301-100 and 13301-1 (Guaranteed In Stock!)

Product Name: DSG Crosslinker

Alternative Names: DSG, discuccinimidyl glutarate, DSG crosslinker, Succinimidyl glutarate, Di(N-succinimidyl) glutarate, 2,5-dioxopyrrolidin-1-yl 6-(2,5-dioxopyrrolidin-1-yl)-5-oxohexanoate; C13H14N2 O8

Specifications

Appearance: White Solid

Purity: is ≥ 97% by quantitative NMR

Storage: 4 °C, protected from moisture

Properties

Properties Physical State: Solid

CAS#: 79642-50-5

Chemical Formula: C13H14N2 O8

Molecular Weight: 326.26

Spacer length: 7.7 Å

Melting Point: 142-145 °C (Lit)

Country of Origin: USA

Tariff Code: 2928.00.5000


Additional Product Information:
DSG Product Information Bulletin
DSG Crosslinker MSDS
  • 2-Iminothiolane

    2-Iminothiolane

    2-Iminothiolane hydrochloride (Traut's Reagent) is used to convert primary amine (-NH2) groups to sulfhydryl groups (-SH) at pH 7 to 10. Traut's reagent (2-IT) is a water soluble molecule that is easy to use and creates a wide range of flexibility to the researcher.
    $69.00
  • Beta-Glucuronidase Solution (100,000 U/mL)

    Beta-Glucuronidase Solution (100,000 U/mL)

    Beta-Glucuronidase solution (β-Glucuronidase) is used in drug testing applications. With our low price of 25 mL for ONLY &36;275, CovaChem is ready to become your #1 supplier of Beta-Glucuronidase.
    $75.00
  • BSA

    BSA

    N,O-bis-(trimethylsilyl) acetamide (BSA) is a silylation reagent used to form stable TMS derivatives that are volatile. BSA is used to derivatize carboxylic acids, phenols, steroids, amines, alcohols, and alkaloids.
    $30.00
  • DHB MALDI Matrix

    DHB MALDI Matrix

    2,5-Dihydroxybenzoic acid (DHB) is a MALDI matrix used in the MALDI-MS of proteins, peptides, synthetic polymers, lipids and carbohydrates.
    $30.00
  • DMF (N,N'-Dimethylformamide)

    DMF (N,N'-Dimethylformamide)

    CovaChem's Molecular Biology Grade DMF is a high purity solvent intended for use in protein assays, chromatography, and other sensitive applications.
    $29.00
  • DMSO (Dimethylsulfoxide)

    DMSO (Dimethylsulfoxide)

    CovaChem's Molecular Biology Grade DMSO is a high purity solvent intended for use in protein assays, chromatography, and other highly sensitive applications.
    $29.00
  • DryBlend PBS (Phosphate Buffered Saline), pH 7.2

    DryBlend PBS (Phosphate Buffered Saline), pH 7.2

    Phosphate buffered saline is used as a buffer in protein crosslinking and protein modification reactions.
    $43.00
  • LC-SPDP Crosslinker

    LC-SPDP Crosslinker

    Succinimidyl 6-[3-(2-pyridyldithio)propionamido] hexanoate (LC-SPDP) is a heterobifunctional crosslinker that is amino reactive on one end and sulfhydryl reactive on the other end. LC-SPDP contains a long spacer arm (15.7 Å)for increased molecular flexibility and a reducible disulfide, which is allows for cleavage of the crosslinker after crosslink formation.
    $197.00
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