DSG Crosslinker

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DSG Crosslinker DSG Crosslinker
Package Sizes: 100 mg
SKU: 13301-100
WEIGHT: 0.20
$32.00
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DSG Crosslinker DSG Crosslinker
Package Sizes: 5 x 100 mg
SKU: 13301-5x100
WEIGHT: 0.20
$140.00
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DSG Crosslinker DSG Crosslinker
Package Sizes: 1 gram
SKU: 13301-1
WEIGHT: 0.20
$259.00
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Disuccinimidyl glutarate (DSG) is a cell membrane permeable, homobifunctional crosslinker with a five carbon spacer arm. DSG contains two NHS esters that are ideal for selectively targeting primary amine moieties at pH 7 to 9. DSG is a simple, short length crosslinker that forms irreversible amide bonds with lysine residues. This compound is ideally suited for a wide range of crosslinking applications, where a cleavable crosslinker is not preferential.

This compound is also available in a water soluble form (BS2G), which enables direct addition to aqueous buffers, when the user prefers not to use any organic solvents in their crosslinking applications.

CovaChem's DSG is among the highest purity in the industry, with an absolute purity specification of ≥ 97%, measured with quantitative NMR against an internal standard, and typical batches have purity values close to 99% pure.

Package Sizes: 100 mg and 1 gram

Product Numbers: 13301-100 and 13301-1

Product Name: DSG Crosslinker

Alternative Names: DSG, discuccinimidyl glutarate, DSG crosslinker, Succinimidyl glutarate, Di(N-succinimidyl) glutarate, 2,5-dioxopyrrolidin-1-yl 6-(2,5-dioxopyrrolidin-1-yl)-5-oxohexanoate; C13H14N2 O8

Specifications

Appearance: White Solid

Purity: is ≥ 97% by quantitative NMR

Storage: 4 °C, protected from moisture

Properties

Properties Physical State: Solid

CAS#: 79642-50-5

Chemical Formula: C13H14N2 O8

Molecular Weight: 326.26

Spacer length: 7.7 Å

Melting Point: 142-145 °C (Lit)

Country of Origin: USA

Tariff Code: 2928.00.5000


Additional Product Information:
DSG Product Information Bulletin
DSG Crosslinker MSDS
  • 2-Iminothiolane

    2-Iminothiolane hydrochloride (Traut's Reagent) is used to convert primary amine (-NH2) groups to sulfhydryl groups (-SH) at pH 7 to 10. Traut's reagent (2-IT) is a water soluble molecule that is easy to use and creates a wide range of flexibility to the researcher.
    $69.00
  • 4-carbethoxyhexafluorobutyrl chloride (4-CB)

    4-carbethoxyhexafluorobutyrl chloride (4-CB) is an alkylation reagent used in GC derivatization for improved gas chromatographic separations.
    $99.00
  • Beta-Glucuronidase Powder

    Beta-Glucuronidase powder (β-Glucuronidase) is used in drug testing applications. With our low price of 250,000 units for ONLY &36;49, CovaChem is ready to become your preferred supplier of Beta-Glucuronidase.
    $49.00
  • BS2G Crosslinker

    BS2G (Sulfo-DSG) is a water soluble amine (amino) reactive homobifunctional crosslinker.
    $89.00
  • D-Biotin

    Biotin is a compound used to biotinylate proteins with the addition of a zero length cross linking reagent. D-Biotin has several biology research applications, where the avidin biotin interaction is utilized.
    $27.00
  • DSP Crosslinker

    Lomant's reagent (DSP) is a reducible homobifunctional crosslinker. Another common name for this reagent is DTSP. DSP contains two NHS esters and contains a disulfide linkage that is cleavable.
    $39.00
  • EGS Crosslinker

    Ethylene glycol bis(succininic acid) N-hydroxysuccinimide ester) is a cleavable, homobifuntional crosslinker that contains two NHS functional groups. The NHS functional groups of EGS are selectively reactive towards primary amines at pH 7 to 9. EGS is cleavable with hydroxylamine at pH 8.5. EGS is often used as a cleavable option when disulfide containing crosslinkers, such as DSP (CovaChem 13304) and DTSSP (CovaChem 13303) are not an option due to the desire to retain disulfide networks of a protein intact.
    $39.00
  • LCMS Grade Acetonitrile

    CovaChem's LCMS Grade Acetonitrile is a high purity solvent ideally suited for LC/MS and other mass spectrometry related applications.
    $73.00
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