|Citraconic Anhydride is a convenient, reversible amine blocking reagent. This protein modification reagent converts primary amines to amide groups with a terminal carboxylic acid moiety.
Citraconic Anhydride reacts with primary amines, such as those found in lysine residues, at pH 7-9. This modification is conveniently reversed at pH 3, rendering a citraconic acid by-product. and returning the amine to its original composition. Alternatively, this reversal can be facilitated in the presence of Hydroxylamine (CovaChem 11304-25).
Package Sizes: 25 grams and 100 grams
Product Numbers: 14105-25 and 14105-100
Product Name: Citraconic Anhydride
Alternative Names: Citraconic anhydride; 2-Methylmaleic anhydride; CAS No. 616-02-4; C5H4O3
Appearance: Clear Liquid
Purity: is ≥ 98% by GC
Storage: 20-25 °C, protected from moisture
Properties Physical State: Liquid
Chemical Formula: C5H4O3
Molecular Weight: 112.08
Boiling Point: 213-214 °C (Lit)
Melting Point: 6-10 °C (Lit)
Density: 1.245 g/mL at 25 °C (Lit)
Refractive Index: 1.47 - 1.472 at 20 °C (Lit)
Tariff Code: 2917.19.7050
IATA Code: 2810
*Important Note: 100 gram size may ship as 4x25 grams to reduce shipping costs.