Description Price Buy
Package Sizes: 100 mg
SKU: 14204-100
WEIGHT: 0.20
Package Sizes: 1 gram
SKU: 14204-1
WEIGHT: 0.20

NHS-SS-Biotin Product Description

NHS-SS-Biotin is a cleavable, long chain amine reactive biotinylation reagent. NHS-SS-Biotin reacts efficiently with compounds containing primary amine (-NH2) residues, including small molecules, proteins, antibodies and other biomolecules.

NHS-SS-Biotin contains a biotin tag, an elongated spacer arm with a reducible disulfide (S-S) and an active NHS ester. This biotinylation compound should be dissolved in a high quality, molecular biology grade, anhydrous solvent, such as DMSO (CovaChem 18252) or DMF (CovaChem 18251) prior to adding to final reaction buffer.

NHS-SS-Biotin labeled proteins can be easily cleaved by exposure to a solution containing TCEP (CovaChem 11303) or DTT (CovaChem 11302).

NHS-SS-Biotin Reaction Mechanism

Package Sizes: 100 mg and 1 gram

Product Numbers: 14204-100; 14204-1

Product Name: NHS-SS-Biotin

Alternative Names: Succinimidyl 2-(biotinamido)-ethyl-1-3’-dithiopropionate; NHS-SS-(+)-Biotin; CAS# 142439-92-7; C19H28N4O6 S3


Appearance: White to Off-White Solid

Purity: is ≥ 90% (Quantitative NMR)

Storage: 4 °C, protected from moisture



Physical State: Solid

CAS#: 142439-92-7

Chemical Formula: C19H28N4O6 S3

Molecular Weight: 504.65

Spacer length: 24.3 Å

Additional Product Information:
NHS SS Biotin Product Information Bulletin

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