2-Mercaptoethanol (2-ME) is a reducing agent used in synthetic and biological applications. This reducing agent is offered in multiple sizes to maximize its efficiency and shelf life. CovaChem's 2-Mercaptoethanol (11301-10 x 1 g) is designed for use in biological assays. These 1 gram hermetically sealed ampules provide maximum protection of the active thiol group and inconsistent activity from use to use or bottle to bottle.
N,O-bis-(trimethylsilyl) acetamide (BSA) is a silylation reagent used to form stable TMS derivatives that are volatile. BSA is used to derivatize carboxylic acids, phenols, steroids, amines, alcohols, and alkaloids.
CHCA MALDI Matrix is a reagent used to create ions for MALDI-MS and MALDI TOF TOF analysis of protein and peptide molecules below 4,000 Daltons. TOF TOF mass spectrometry is one of the more common forms of MALDI-MS/MS, although several other types of mass spectrometers can also be coupled to MALDI instrumentation.
Ethylene glycol bis(succininic acid) N-hydroxysuccinimide ester) is a cleavable, homobifuntional crosslinker that contains two NHS functional groups. The NHS functional groups of EGS are selectively reactive towards primary amines at pH 7 to 9. EGS is cleavable with hydroxylamine at pH 8.5. EGS is often used as a cleavable option when disulfide containing crosslinkers, such as DSP (CovaChem 13304) and DTSSP (CovaChem 13303) are not an option due to the desire to retain disulfide networks of a protein intact.
N-(∑-Maleimidocaproyloxy) succinimide ester(EMCS) is a heterobifunctional crosslinker with a spacer length of 9.4 Å. EMCS contains an amine reactive, NHS ester, and a maleimide group which is reactive towards sulfhydryl functional groups.