CovaChem's LCMS Grade Acetic Acid is ideally suited as a chromatography additive for use in both HPLC and LCMS applications. Acetic acid is typically beneficial as a separations enhancer, and has a weak ion pairing effect in the mass spectrometer, making dissociation of from the analytes relatively easy, often resulting in increased ionization efficiencies. CovaChem's LCMS Grade Acetic Acid comes in two convenient package sizes (10 x 1 mL Ampules and 25 mL bottles). The 1 mL Ampules of LCMS Grade Acetic Acid are useful for quickly preparing 1 Liter bottles of 0.1% Acetic Acid solutions in either water or other organic solvents.
Package Sizes: 10 x 1 mL and 25 mL
Product Numbers: 11201-10x1 or 11201-25
Hydroxylamine Hydrochloride (Hydroxylamine HCl) is a widely used reducing agent used in biomolecular applications. Hydroxylamine HCl is used for reducing EGS crosslinkers and deprotecting SATA protected proteins.
N-Ethoxycarbonylmaleimide is used in synthetic applications and in protein reactions. This compound can be used in reactions involving Diel-Alder reactions, Michael additions and can be utilized to introduce a maleimide group into a peptide or protein.
N-succinimidyl-3-(2-pyridyldithio)propionate (SPDP Crosslinker) is a heterobifunctional crosslinker. SPDP has a dithiopyridyl group which is reactive towards cyteines (-SH groups) and a NHS group, which can be used to target primary amines (-NH2 groups. Additionally, SPDP contains a disulfide linkage in its spacer arm, which can be reduced by a reducing agent, such as DTT, TCEP, among a few others carried by CovaChem.