Silylation

  • BSA

    N,O-Bis(trimethylsilyl) acetamide (BSA) is a silylation reagent used to form stable trimethylsilyl (TMS) derivatives that are volatile. CovaChem's BSA is GC and GC/MS derivatization grade, and is commonly used for the derivatization of polar functional groups, such as carboxylic acids, phenols, steroids, amines, alcohols, and alkaloids and amides. This reagent is ideally suited to form derivatives with smaller molecules. .

    Package Sizes: 10 x 1 g, 25 g, 100 g

    Product Numbers: 12101-10x1, 12101-25, and 12101-100

    Product Name: BSA

    Alternative Names: N,O-Bis-trimethylsilyl acetamide; BSA

    Specifications

    Appearance: Clear and colorless liquid

    Purity: is ≥ 98.0%

    Storage: 20 °C, protected from moisture

    Properties

    Properties Physical State: Clear liquid

    CAS#: 10416-59-8

    Chemical Formula: C9H21NOSi2

    Molecular Weight: 203.43

    Density: 0.832 at 20 °C (Lit)

    Boiling Point: 71-73 °C (Lit)

    Refractive Index: n20/D 1.417 (Lit)

    Tariff Code: 2931.90.9010

    $30.00
  • BSTFA

    N,O-Bis(trimethylsilyl)trifluoroacetamide (BSTFA) is a versatile silylation reagent used to form stable trimethylsilyl derivatives that are volatile. CovaChem's BSTFA is GC and GC/MS derivatization grade, and is routinely used to derivatize carboxylic acids, phenols, steroids, amines, alcohols, and alkaloids and amides. This reagent is ideally suited to form derivatives with smaller molecules. This reagent is available with or without the TMCS catalyst.

    Package Sizes: 10 x 1 g, 25 g, 100 g

    Product Numbers (without TMCS): 12102-10x1, 12102-25, and 12102-100

    Product Numbers (with 1% TMCS): 12102T-10x1, 12102T-25, and 12102T-100

    Product Name: BSTFA

    Alternative Names: N,O-Bis(trimethylsilyl)trifluoroacetamide; BSTFA derivitization reagent; C9H18F3NO Si

    BSTFA (CAS# 25561-30-2) ampules-silylation for GC

    Specifications

    Appearance: Clear and colorless liquid

    Purity: is ≥ 99%

    Storage: 20 °C, protected from moisture

    Properties

    Properties Physical State: Clear liquid

    CAS#: 25561-30-2

    Chemical Formula: C9H18F3NO Si

    Molecular Weight: 257.4

    Density: 0.969 at 25 °C (Lit)

    Boiling Point: 45-50 °C (Lit)

    Refractive Index: n20/D 1.384 (Lit)

    Tariff Code: 3822.00.0000


    Additional Product Information:
    BSTFA Product Information Bulletin
    BSTFA MSDS

    $34.00
  • MSTFA

    N-Methyl-N-(trimethylsilyl)trifluoroacetamide (MSTFA) is a silylation reagent, that donates a trimethylsilyl group to create thermally stable derivatives. MSTFA is reacts with a variety of polar molecules by replacing labile hydrogens. TMCS can be used in addition to MSTFA to form derivatives with hindered hydroxyl groups that won't ordinarily react with MSTFA, secondary amines, and amides. This reagent is available with or without the TMCS catalyst


    Package Sizes: 10 x 1 g, 25 g and 100 g

    MSTFA Product Numbers: 12104-10x1, 12104-25 and 12104-100

    MSTFA w/ 1% TMCS Product Numbers: 12104T-10x1; 12104T-25; 12104T-100


    Product Name(s): MSTFA and MSTFA with 1% TMCS

    Alternative Names: MSTFA derivitization reagent; N-Methyl-N-(trimethylsilyl)trifluoroacetamide; N-Trimethylsilyl-N-methyl trifluoroacetamide; MSTFA with 1% TMCS


    Specifications

    Appearance: Clear and colorless liquid

    Purity: is ≥ 98 %

    Storage: 20 °C, protected from moisture


    Properties

    Physical State: Liquid

    Chemical Formula: C6H12F3NOSi

    Molecular Weight: 199.25

    Boiling Point: 70 °C (Lit)

    Density: 1.11


    Additional Product Information:
    MSTFA Product Information Bulletin
    MSTFA MSDS

    $34.00
  • MTBSTFA

    N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide (MTBSTFA) is a derivatization reagent used to silylate carboxyl, hydroxyl, primary amines, secondary amines and thiol (-SH) functional groups. MTBSTFA derivatization reactions go to completion typically in 15 minutes or less, and the products formed are volatile. One of the key benefits of MTBSTFA is that the derivative products formed from the reaction with MTBSTFA are roughly 10,000 times more stable than traditional TMS ethers. This derivatization reagent is available with the 1% TBDMCS catalyst and without.

    Package Sizes: 10 x 1 g, 25 g, 100 g

    Product Numbers (without TBDMCS): 12107-10x1, 12107-25, and 12107-100

    Product Numbers (with 1% TBDMCS): 12107T-10x1, 12107T-25, and 12107T-100

    Product Name: MTBSTFA

    Alternative Names: N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide; MTBSTFA derivatization reagent; MTBSTFA with 1% TBDMCS; C9H18F3NO Si

    Specifications

    Appearance: Clear and colorless liquid

    Purity: is ≥ 99%

    Storage: 20 °C, protected from moisture

     

    Properties Physical State: Clear liiquid

    CAS#: 77377-52-7

    Chemical Formula: C9H18F3NO Si

    Molecular Weight: 241.33

    Tariff Code: 2931.90.9010

    $45.00
  • TMCS

    Trimethychlorosilane (TMCS) is used to catalyze difficult to silylate compounds. This reagent is commonly used to create trimethylsilyl esters from organic acids. TMCS can be used in addition to MSTFA to form derivatives with hindered hydroxyl groups that won't ordinarily react with MSTFA (CovaChem 12104)

    Package Sizes: 10 x 1 g, 25 g and 100 g.
    Product Numbers: 12109-10x1, 12109-25, and 12109-100

    Product Name: TMCS
    Alternative Names: Trimethylchlorosilane; Chlorotrimethylsilane; TMCS derivatization grade; TMCS derivatization reagent;

    Specifications
    Appearance: Clear and colorless liquid
    Purity: is ≥ 99.5 %
    Storage: 20 °C, protected from moisture.

    Properties
    Physical State: Liquid
    Chemical Formula: C3H9ClSi
    Molecular Weight: 108.64
    Boiling Point: 57.6 °C (Lit)
    Density: 0.858

    $30.00
  • TMSI-N-Trimethylsilylimidazole

    TMSI (N-Trimethylsilylimidazole) is a derivatization reagent used to silylate hydroxyl groups and carboxylic acids. TMSI is highly reactive and does not derivatize amines, allowing for a more selective derivatization reactions. This feature of TMSI is particularly useful for approaches where multiple types of derivatives are preferred.

    Package Sizes: 10 x 1 g, 25 g, 100 g

    Product Numbers: 12108-10x1, 12108-25, and 12108-100

    Product Name: TMSI

    Alternative Names: Trimethylsilylimidazole; TMSI; TSIM; C6H12N2Si

    Specifications

    Appearance: Clear and colorless liquid

    Purity: is ≥ 99%

    Storage: 20 °C, protected from moisture

     

    Properties Physical State: Clear liiquid

    CAS#: 18156-74-6

    Chemical Formula: C6H12N2Si

    Molecular Weight: 140.26

    $44.00